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O-PCE Crystal
O‐PCE (in full: 2-oxo-PCE, also known as eticyclidone) is a potent dissociative drug belonging to the arylcyclohexylamine family, as is ketamine, MXE, and PCP. It is a non-medical, illegally dissociative agent that mainly circulates in the research chemical market.
🔬 What is O‐PCE?
Full name: 2-Oxo-PCE (2-oxo-N-ethyl-1-phenylcyclohexanamine)
Chemically related to: Ketamine, deschloroketamine (DCK), MXE
Mechanism of action: NMDA receptor antagonist → blockage of glutamate transmission → dissociation, anesthetic, hallucinations
⚡ Effects (subjective):
Effect type | Description |
Dissociation | Body awareness disappears, feeling of “being disconnected” |
Euphoria | Possible at lower dosages |
Cognitive alienation | Thoughts feel strange or disturbed |
Sensory | Visual disturbances, blur, time distortion |
Physical | Movement disorders, loss of coordination |
🕒 Start: 15–45 minutes⏳ Duration: 3–6 hours🌙 Aftermath: “Afterglow” or “mist” possible up to 24 hours
💊 Dosage (for information only – not recommended):
Administration Form | Light | Average | High |
Oral | 5–10 mg | 10–20 mg | 20–30+ mg |
Nasal | 3–6 mg | 6–15 mg | 15–25+ mg |
❗ The effective dosage is low – overdose hazard is real, especially with nasal intake.The experience is intense and unpredictable.
⚠️ Risks:
Blackouts, memory loss
Involuntary movements or injuries
Urinary tract problems, such as in ketamine (leaf toxicity)
Neurotoxicity (possibly with chronic use)
Psychosis, depersonalization or derealization at high or repeated doses
Addiction risk with frequent use
🚫 Combination with alcohol, GHB, benzos or opioids can be fatal.
✅
Measure | Why |
Start with microdose | E.g. 3 mg oral to test sensitivity |
No combinations | With downers or other dissociatives = danger |
Provide safe space | You lose control of body & environment |
Use with tripsitter | Essential at first time or higher dose |
Hydrating & resting | Essential with prolonged aftermath |
🧠 Summary:
Characteristic | Content |
Name | O-PCE (2-oxo-PCE / Eticyclidone) |
Type | Dissociative means |
Operation | NMDA antagonist |
Form | Crystal/Powder |
Effect duration | 3–6 hours |
Risks | Blackouts, injuries, bladder problems, addiction |
O-PCE properties
Synonym: 2′-oxo-PCE, eticyclidone hydrochloride CAS Number: 4551-92-2 Formula: 2-(ethylamino)-2-phenyl-cyclohexanone hydrochloride Molmass: 253.8 g/mol Purity: >97%
AVAILABLE ONLY AT GOLDSMOKE.net
Our products are intended for research purposes only.
The sale of our products is only permitted to persons 18 years and older.
Human consumption is not allowed and is emphatically discouraged.
We do not provide personal advice on the use of research chemicals. There is therefore no point in contacting us by e-mail
The products are not intended for medical, clinical, commercial or consumer applications.
In case of problems with substance use, we advise you to contact a general practitioner or other professional assistance.
See also: https://psychonautwiki.org/wiki/Responsible_drug_use

