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Information
A-PVP is chemically the ketone analog of proline. Physically, it is an odorless, colorless solid crystal form. α-PVP is also chemically called α-pyrrolidinovalerophenone, 1-Phenyl-2- (pyrrolidine-1-yl) pentane-1-one, α-Pyrrolidinopentiophenone.
Pharmacology and Effects
A-PVP is a synthetic cathinone that functions as a potent inhibitor of dopamine and norepinephrine reuptake, leading to strong stimulant effects. It produces increased alertness, euphoria, and psychomotor activation similar to other pyrrolidinophenones such as MDPV.
Mechanism of action: Dopamine and norepinephrine reuptake inhibitor
Receptor targets: DAT > NET (no significant serotonergic activity)
Onset: Rapid, within minutes
Duration: 2–4 hours (variable)
Reported effects: Stimulation, euphoria, increased energy
Potency: High, active at low milligram doses
Risks and Side Effects
A-PVP has been linked to severe adverse effects including agitation, paranoia, tachycardia, and hyperthermia. Toxic overdoses and fatalities have been reported, especially when used in high doses or combined with other stimulants.
Cardiovascular: Tachycardia, hypertension, chest pain
Neurological: Agitation, tremors, seizures
Psychiatric: Anxiety, paranoia, hallucinations
Thermoregulatory: Hyperthermia, dehydration
Toxicity: Documented cases of severe intoxication and death
Dependence potential: High, with strong craving behavior
Warning
The use of A-PVP may pose serious health risks. It is strongly discouraged for recreational use.
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Our products are intended for research purposes only.
The sale of our products is only permitted to persons 18 years and older.
Human consumption is not allowed and is emphatically discouraged.
We do not provide personal advice on the use of research chemicals. There is therefore no point in contacting us by e-mail
The products are not intended for medical, clinical, commercial or consumer applications.
In case of problems with substance use, we advise you to contact a general practitioner or other professional assistance.
See also: https://psychonautwiki.org/wiki/Responsible_drug_use